Senolytic Supplement Database 2026
A source-backed comparison of 21 current fisetin and senolytic products. Phase 3 adds proprietary transparency, value, evidence-match and stack-complexity scores while keeping those scores separate from clinical efficacy.
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Phase 3 market snapshot
21 products
Current single-ingredient, enhanced-bioavailability and multi-senolytic products in the expanded database.
8–1,500 mg
Verified fisetin per stated serving across 18 entries. Median: 112.5 mg.
10/21 testing disclosures
Entries where the reviewed source explicitly disclosed testing or comparable retailer verification.
Why the scores matter
Transparency Score rewards dose, serving, price, testing, COA and manufacturing disclosure. Fisetin Value Score is a price-density comparison where usable dose and price are both captured. Evidence Match Score asks how cleanly the commercial formula maps to the ingredient being discussed in research. Stack Complexity describes formula breadth. None of these scores predicts health outcomes.
Read the scoring methodology · See the Fisetin Value Index · See the testing transparency report
Product comparison database
| Product | Type | Fisetin/serving | Price | Cost/100 mg | Delivery | Testing | COA | Transparency | Value | Evidence Match | Complexity | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Doctor's Best Fisetin with Novusetin | Single-ingredient | 100 mg | $22.99 | $22.99 | Standard capsule / Novusetin source | Not captured | Not captured | 5/10 | 4.9/10 | 8/10 | 1/5 | Source |
| Double Wood Fisetin Supplement | Single-ingredient | 100 mg | $22.92 | $22.92 | Standard capsule | Yes | Yes | 10/10 | 4.9/10 | 9/10 | 1/5 | Source |
| ProHealth Longevity Pure Fisetin | Single-ingredient | 250 mg | $55.95 | $22.38 | Standard capsule | Yes | Yes | 10/10 | 5.0/10 | 9/10 | 1/5 | Source |
| ProHealth Longevity Fisetin Pro Longevity Plus | Enhanced / multi-active | 125 mg | $37.95 | $30.36 | Absorption blend + MCT oil powder | Not separately captured | Yes | 7/10 | 4.3/10 | 7/10 | 4/5 | Source |
| ProHealth Longevity Rapid Reset Multi-Senolytic | Multi-senolytic stack | 1,500 mg | $69.95 | $4.66 | Multi-ingredient pulse formula | Yes | Yes | 10/10 | 8.3/10 | 7/10 | 5/5 | Source |
| Life Extension Bio-Fisetin | Enhanced-bioavailability | 8 mg | $11.25 | $140.62 | Fenugreek galactomannan delivery system | Not captured | Not captured | 5/10 | 1.0/10 | 6/10 | 2/5 | Source |
| Toniiq Fisetin 500 | Enhanced / high-purity | 500 mg | $44.97 | $8.99 | MCT oil-assisted capsule formulation | Yes | Yes | 10/10 | 6.9/10 | 8/10 | 2/5 | Source |
| Toniiq Senolytic+ 4000 | Multi-senolytic stack | 1,400 mg | $29.97 | $2.14 | Multi-ingredient pulse / maintenance formula | Yes | Yes | 10/10 | 10.0/10 | 7/10 | 5/5 | Source |
| Toniiq Qova | Broad longevity stack | 50 mg | $55.00 | $110.00 | Powder / multi-pathway formula | Yes | Yes | 10/10 | 1.5/10 | 7/10 | 5/5 | Source |
| DoNotAge.org Pure Fisetin | Single-ingredient | 400 mg | $95.00 | $23.75 | Standard capsule | Brand site says third-party tested | Not captured | 6/10 | 4.8/10 | 8/10 | 1/5 | Source |
| Renue By Science LIPO Fisetin | Liposomal | Not verified | $64.95 | — | Liposomal formulation | Yes | Yes | 7/10 | — | 6/10 | 2/5 | Source |
| Nature's Fusions Nutri Fisetin Extra Strength | Single-ingredient / high-dose | 500 mg | $48.99 | $9.80 | Standard capsule | Not captured | Not captured | 4/10 | 6.7/10 | 6/10 | 1/5 | Source |
| California Gold Nutrition Fisetin with Novusetin | Single-ingredient | 100 mg | $36.69 | $36.69 | Novusetin fisetin capsule | iTested / retailer verification | Not captured | 8/10 | 3.9/10 | 9/10 | 1/5 | Source |
| California Gold Nutrition Fisetin with BeFisetin | Single-ingredient | 100 mg | $21.74 | $21.74 | BeFisetin from Rhus cotinus L. | iTested verified | Not captured | 8/10 | 5.0/10 | 9/10 | 1/5 | Source |
| Neurogan Health Fisetin | Single-ingredient / high-dose | 500 mg | $22.36 | $4.47 | Standard capsule | Not captured | Not captured | 4/10 | 8.4/10 | 6/10 | 1/5 | Source |
| Nutricost Fisetin | Single-ingredient | 100 mg | $21.95 | $21.95 | Standard capsule | Not captured | Not captured | 4/10 | 5.0/10 | 6/10 | 1/5 | Source |
| Swanson Vitamins Fisetin Novusetin | Single-ingredient | 100 mg | $17.89 | $17.89 | Novusetin capsule | Not captured | Not captured | 4/10 | 5.4/10 | 7/10 | 1/5 | Source |
| Humanx Fisetin | Single-ingredient / high-dose | 500 mg | $54.95 | $10.99 | Standard capsule | Not captured | Not captured | 4/10 | 6.5/10 | 6/10 | 1/5 | Source |
| Vitacost Fisetin Flavonoid | Single-ingredient | 100 mg | $11.96 | $11.96 | Standard capsule | Not captured | Not captured | 5/10 | 6.3/10 | 7/10 | 1/5 | Source |
| Dr. Mercola Fisetin and Spermidine | Multi-active | Not verified | $62.49 | — | Combination capsule | Not captured | Not captured | 2/10 | — | 2/10 | 4/5 | Source |
| Elysium Senolytic Complex | Multi-senolytic stack | Not verified | $60.00 | — | Multi-ingredient senolytic complex | Not captured | Not captured | 2/10 | — | 2/10 | 5/5 | Source |
What the expanded sample shows
The market is not standardized. Some products sell 100 mg conventional capsules; others sell 500 mg high-dose capsules; enhanced-bioavailability products may use much smaller nominal amounts; and multi-senolytic stacks can contain more than a gram of fisetin inside a short-duration protocol. Comparing milligrams alone is therefore a crude buying method.
Price density also varies sharply. Phase 3 calculates it only when the database contains both a current captured price and a verified fisetin amount. Multi-active formulas and entries with missing dose fields are deliberately left unscored rather than forced into a fake ranking.
Why the database exists
Narrative product reviews are difficult to audit. The database turns product comparisons into explicit fields such as dose, price, serving size, testing, COA visibility, formulation, and stack structure.
What is included
The current database covers focused Fisetin products, liposomal and enhanced-bioavailability products, higher-dose options, and broader senolytic or longevity stacks.
Why missing data stay missing
When a current source does not expose a dose, price, test document, or certification, the database records that gap rather than filling it from old snippets or assumptions.
Transparency Score
Transparency rewards clear dose, testing, COA availability, serving structure, ingredient source, price visibility, and manufacturing disclosure. It measures auditability rather than efficacy.
Fisetin Value Score
Value Score applies only where enough verified dose and price data exist to support a normalized comparison. It does not imply that the cheapest milligram is the best product.
Evidence Match
Evidence Match asks how closely a commercial product maps to the ingredient discussed in the literature. Focused formulas are often easier to evaluate than complicated blends.
Stack Complexity
Complexity describes how many active components a formula contains. More complexity means more questions about dose sufficiency, overlap, interactions, and finished-formula evidence.
How the database will evolve
Future updates can add more brands, historical price tracking, standardized testing fields, subscriptions, refund policies, and finished-formula human-study data.
Update trigger 1
For Senolytic Supplement Database 2026, the conclusion should remain open to revision. New human studies, formula changes, updated COAs, price changes, and newly disclosed testing can all alter the commercial recommendation. The useful goal is not to create a permanent winner, but to make the comparison transparent enough that readers can see why the conclusion was reached and what evidence would change it.
Update trigger 2
For Senolytic Supplement Database 2026, the conclusion should remain open to revision. New human studies, formula changes, updated COAs, price changes, and newly disclosed testing can all alter the commercial recommendation. The useful goal is not to create a permanent winner, but to make the comparison transparent enough that readers can see why the conclusion was reached and what evidence would change it.